港股生物技术板块持续走强，来凯医药(02105.HK)、康希诺生物(06185.HK)涨超20%，北海康成(01228.HK)涨超14%，轩竹生物-B(02575.HK)、百奥赛图-B(02315.HK)涨8%。

Spreads on US CCC-rated corporate bonds over Treasuries exceeded 1,000 bps, up from about 860 bps in early September and the widest since the 2023 regional bank crisis when investors sold high-risk credit. Such risk premia typically indicate elevated odds of default, restructuring or losses. Collin Martin, head of fixed-income research and strategy at Charles Schwab Wealth Management, said the main driver is an economy that is performing adequately but not robustly; CCC issuers are the riskiest and most sensitive to interest-rate moves.

Al Arabiya reported that over the past 24 hours Yemeni government forces' drones repeatedly struck Houthi fighters, assembly areas across multiple fronts, reinforcements and equipment.