Nonprofit biomedical research organization Biohub said new investments from Google (GOOG.O) and others raised its total funding to $1.8 bln.

European equities opened softer Wednesday, diverging from overnight US record highs. Brent crude rose back above $100/bbl on Houthi attacks on Saudi Arabia and a Gulf of Mexico storm that raised supply concerns. The 10-year US Treasury yield topped 5.30%, refocusing markets on inflation and higher-rate pressures; France's 10-year yield briefly eased after far-right leader Le Pen pledged spending cuts but later rebounded to 4.83%. US futures were subdued — S&P 500 futures flat, Nasdaq futures down 0.1% — as investors await a $3.9 bln US 10-year auction and the Fed's September minutes.

HKEX filing shows BlackRock's long position in COSCO Shipping Energy Transportation (01138.HK) H‑shares rose to 7.27% on Oct. 2 from 6.07%.