Ailes said the overseas Phase III FURVENT study of its core drug Fumetinib
requires deeper data analysis and the company will finalize subsequent
development and regulatory engagement after review. The company expects the
FURVENT result will not affect Fumetinib sales in Q3 or thereafter, noting
current revenue is driven by its first‑line indication for EGFR sensitizing
mutations. At a global investigators’ meeting, experts judged Fumetinib met
prior efficacy expectations for EGFR exon 20 insertion mutations. A blinded
independent central review (BICR) found a substantial divergence in PFS versus
investigator assessment in the chemotherapy arm; excluding that discrepancy, the
company said other data performed well.