Nonprofit biomedical research group Biohub said the U.S. government, Google (GOOG.O) and Meta Platforms (META.O) will join Biohub in a joint investment in AI biological data.

Singapore's foreign-exchange reserves were $433.4 bln in September, versus $432.97 bln previously.

European equities opened softer Wednesday, diverging from overnight US record highs. Brent crude rose back above $100/bbl on Houthi attacks on Saudi Arabia and a Gulf of Mexico storm that raised supply concerns. The 10-year US Treasury yield topped 5.30%, refocusing markets on inflation and higher-rate pressures; France's 10-year yield briefly eased after far-right leader Le Pen pledged spending cuts but later rebounded to 4.83%. US futures were subdued — S&P 500 futures flat, Nasdaq futures down 0.1% — as investors await a $3.9 bln US 10-year auction and the Fed's September minutes.