[CR Double-Crane: Hydroxycobalamin Injection Receives Clinical Trial Approval] CR Double-Crane announced that it recently received the "Drug Clinical Trial Approval Notice" for its hydroxycobalamin injection issued by the National Medical Products Administration. The notice indicates that hydroxycobalamin injection is suitable for the treatment of metabolic disorders in children with methylmalonic acidemia with or without homocysteineemia. The company received the acceptance notice on October 22, 2025, and the "Drug Clinical Trial Approval Notice" on December 25, 2025. As of the date of this announcement, the company's cumulative R&D investment in this drug is RMB 13,058,100 (unaudited).