Conference data published Saturday show Amgen’s Imdelltra combined with AstraZeneca’s Imfinzi cuts the risk of death by 58% versus Imfinzi alone in extensive‑stage small‑cell lung cancer. Median overall survival was 21.1 months for the combo versus 1

2026-10-24

Conference data published Saturday show Amgen’s Imdelltra combined with AstraZeneca’s Imfinzi cuts the risk of death by 58% versus Imfinzi alone in extensive‑stage small‑cell lung cancer. Median overall survival was 21.1 months for the combo versus 12.7 months for Imfinzi monotherapy. Imfinzi is currently the post‑chemotherapy standard for patients without progression after first‑line chemo. Amgen CMO Paul Burton said earlier use of Imdelltra produced greater clinical benefit and called the result unprecedented for advancing treatment in this indication.